Every ingredient claim we score, graded A–F on the strength of the peer-reviewed research behind it. Search, filter and jump to the studies.
| Compare | Claim | Grade |
|---|---|---|
| Lower oxidation risk than large-fish oil Short-lived species carry less heavy-metal load and typically fresher on shelf. View studies & products → | ASave |
| Compare | Claim | Grade |
|---|---|---|
| Neurologic and retinal development in puppies Diets enriched with DHA improve trainability and visual acuity in puppies. View studies & products → | ASave |
| Compare | Claim | Grade |
|---|---|---|
| Anti-inflammatory joint benefit in dogs Active omega-3 responsible for most of the OA effect; dose reported per EPA content. View studies & products → | ASave |
| Compare | Claim | Grade |
|---|---|---|
| Reduces clinical signs of osteoarthritis in dogs Multiple randomised controlled trials show improved weight bearing, owner-assessed lameness and ability to rise at ~50–100 mg EPA+DHA / kg / day. View studies & products → | ASave | |
| Improves skin/coat and reduces pruritus in atopic dogs Consistent modest benefit as adjunctive therapy; effect size smaller than for OA. View studies & products → | BSave | |
| Slows cognitive decline in senior dogs Small canine studies suggestive; strongest evidence is from broader nutrient blends. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Same benefits as fish oil at label EPA/DHA dose Bioequivalent when EPA+DHA dose is matched; sourcing and freshness matter more than species. View studies & products → | ASave |
| Compare | Claim | Grade |
|---|---|---|
| Essential for bone, immune and cardiac health Deficiency and excess both harmful; supplement only when a diet is measured-deficient. View studies & products → | ASave |
| Compare | Claim | Grade |
|---|---|---|
| Adds modest benefit when combined with glucosamine Best evidence is combined formulations; monotherapy data are weaker. View studies & products → | BSave |
| Compare | Claim | Grade |
|---|---|---|
| Reduces mild-to-moderate OA signs in dogs Meta-analyses show a small but real benefit; effect is smaller than NSAIDs and slower to onset. View studies & products → | BSave |
| Compare | Claim | Grade |
|---|---|---|
| Reduces OA pain and joint swelling Several canine trials support use at ~30 mg/kg/day of stabilised powder. View studies & products → | BSave |
| Compare | Claim | Grade |
|---|---|---|
| Comparable OA benefit to fish oil per mg EPA+DHA Small trials show similar outcomes; higher cost per mg omega-3 in Canada. View studies & products → | BSave |
| Compare | Claim | Grade |
|---|---|---|
| General gut and immune support Effects depend on strain identity, CFU at expiry, and delivery survival. View studies & products → | BSave |
| Compare | Claim | Grade |
|---|---|---|
| Reduces dental plaque and calculus in dogs Multiple RCTs on the ProDen PlaqueOff strain show plaque/tartar reduction. View studies & products → | BSave |
| Compare | Claim | Grade |
|---|---|---|
| Reduces acute and antibiotic-associated diarrhoea in dogs Randomised canine data support use for AAD and stress diarrhoea. View studies & products → | BSave |
| Compare | Claim | Grade |
|---|---|---|
| Hepatoprotective; helps in copper and steroid hepatopathy Multiple canine studies support use, often combined with silybin. View studies & products → | BSave |
| Compare | Claim | Grade |
|---|---|---|
| Improves lameness scores comparable to glucosamine+chondroitin Small canine RCTs (40 mg/day) show improvement in force-plate and owner scores. View studies & products → | BSave |
| Compare | Claim | Grade |
|---|---|---|
| Antioxidant support especially with high PUFA diets Requirement rises with fish/omega-3 intake. View studies & products → | BSave |
| Compare | Claim | Grade |
|---|---|---|
| Reduces stress-associated diarrhoea (strain AHC7) Strain-specific canine RCTs support this; not all Bifido products are equivalent. View studies & products → | BSave |
| Compare | Claim | Grade |
|---|---|---|
| Palatability, hydration and modest gelatin/amino acid content No strong disease-modifying evidence; safe when made without onion/garlic/excess salt. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Reduces OA signs in dogs Old open-label canine study showed benefit; better human evidence in OA. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Adjunct in canine cardiomyopathy Small canine data; often used empirically alongside standard cardiology treatment. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Modulates immune and gut markers Small studies; effect sizes modest and variable by source. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Reduces recurrent bacterial UTI risk Some evidence via anti-adhesion; not a treatment for active UTI. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Meaningful benefit only in EPI-diagnosed dogs Otherwise limited benefit in normal dogs on complete diets. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Palatability and moisture-free convenience Nutritional benefit depends on the base diet; pathogen risk exists in raw formats. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Palatability and probiotic delivery (if raw/fermented) Modest evidence for tolerance vs cow milk; not a meaningful nutrient source. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Reduces situational anxiety in dogs Open-label and small blinded studies suggest benefit for storm/travel anxiety. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Improves stool quality in healthy dogs Strain-specific; general genus claims are weak. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Cognitive and nerve-growth-factor support Rodent and human pilot data; no controlled canine trials yet. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Aids sleep and reduces noise-phobia signs Mostly clinical experience and small case series; behavioural plan should be first-line. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Hepatoprotective adjunct for liver disease Silybin-phosphatidylcholine complexes have the best pharmacokinetic data in dogs. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Adjunctive OA pain relief Mostly extrapolated from human OA trials; limited dog-specific RCTs. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Improves faecal microbiome diversity Short-chain FOS/inulin evidence is largely surrogate-marker based. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| General immune modulation Mostly in-vitro and rodent data; canine outcome data limited. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Extended survival in canine hemangiosarcoma (small study) Single small trial (Brown 2012, PSK 100 mg/kg); results have not been replicated at scale. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Adjunctive anti-inflammatory effect in canine OA Bioavailability is the main limit; results are mixed and formulation-dependent. View studies & products → | CSave |
| Compare | Claim | Grade |
|---|---|---|
| Source of iodine and trace minerals Iodine content is highly variable batch-to-batch; risk of over-supplementation. View studies & products → | DSave |
| Compare | Claim | Grade |
|---|---|---|
| Anti-inflammatory / odour-reduction claims Mostly in-vitro and anecdotal; safety concerns at high doses. View studies & products → | DSave |
Educational information only. Not veterinary advice. Always talk to your vet before starting a new supplement.