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Evidence DatabaseSaved evidence
Claim evidence

Aids sleep and reduces noise-phobia signs

Grade CLimited or mixed evidenceSave claim
Ingredient: Melatonin · calming

Plain-language summary

Mostly clinical experience and small case series; behavioural plan should be first-line.

About the ingredient

What it is

Hormone involved in sleep regulation.

Why it's used

Marketed for calming/sleep support.

Also known as: Melatonin

Cited studies (4)

Canine studies
  • Melatonin Supplementation for the Cryopreservation of Canine Sperm.
    Monteiro KS, Motta NC, Cardoso ACP, Souza SP, Murgas LDS · Biopreservation and biobanking · 2023
    Study summary
    Very limited quality
    Design score 2/11
    Design
    Journal Article
    Species
    dog
    Sample size
    Not reported
    Duration
    Not reported
    Controls / blinding
    Not reported
    Funding
    Not reported
    Strengths
    • Conducted in dogs
    Limitations
    • Sample size not recorded
    • No control group recorded
    • Study duration not recorded

    Relevance to this claim: Ingredient-level evidence for Melatonin

  • Essential Oils and Melatonin as Functional Ingredients in Dogs.
    Ruiz-Cano D, Sánchez-Carrasco G, El-Mihyaoui A, B Arnao M · Animals : an open access journal from MDPI · 2022
    Study summary
    Very limited quality
    Design score 2/11
    Design
    Journal Article; Review
    Species
    dog
    Sample size
    Not reported
    Duration
    Not reported
    Controls / blinding
    Not reported
    Funding
    Not reported
    Strengths
    • Conducted in dogs
    Limitations
    • Sample size not recorded
    • No control group recorded
    • Study duration not recorded

    Relevance to this claim: Ingredient-level evidence for Melatonin

  • Serum Melatonin Values in Normal Dogs and Dogs with Seizures.
    Thomovsky SA, Chen AV, Deavila DM, Kiszonas AM · Journal of the American Animal Hospital Association · 2019
    Study summary
    Very limited quality
    Design score 2/11
    Design
    Journal Article
    Species
    dog
    Sample size
    Not reported
    Duration
    Not reported
    Controls / blinding
    Not reported
    Funding
    Not reported
    Strengths
    • Conducted in dogs
    Limitations
    • Sample size not recorded
    • No control group recorded
    • Study duration not recorded

    Relevance to this claim: Ingredient-level evidence for Melatonin

  • Study summary
    Very limited quality
    Design score 2/11
    Design
    case series
    Species
    dog
    Sample size
    Not reported
    Duration
    Not reported
    Controls / blinding
    Not reported
    Funding
    Not reported
    Strengths
    • Conducted in dogs
    Limitations
    • Case-level observation only
    • Sample size not recorded
    • No control group recorded
    • Study duration not recorded

    Outcome: Owner-reported reduction in fear responses

Products in our catalog with Melatonin (1)

Educational information only. Not veterinary advice. Grades reflect published dog research and reviewer consensus, not marketing.