Evidence DatabaseSaved evidence
Claim evidence

Hepatoprotective adjunct for liver disease

Grade CLimited or mixed evidenceSave claim
Ingredient: Milk Thistle · botanical

Plain-language summary

Silybin-phosphatidylcholine complexes have the best pharmacokinetic data in dogs.

About the ingredient

What it is

Herb standardized for silymarin.

Why it's used

Marketed for liver support.

Also known as: Silybum marianum, Silymarin

Cited studies (1)

Canine studies
  • Silybin-phosphatidylcholine complex pharmacokinetics in dogs
    American Journal of Veterinary Research · 2005
    Save studyB
    Study summary
    Limited quality
    Design score 3/11
    Design
    PK study
    Species
    dog
    Sample size
    Not reported
    Duration
    Not reported
    Controls / blinding
    Not reported
    Funding
    Not reported
    Strengths
    • Conducted in dogs
    Limitations
    • No blinded control group
    • Sample size not recorded
    • No control group recorded
    • Study duration not recorded

    Outcome: Absorbable form validated for hepatic use

Products in our catalog with Milk Thistle (1)

Educational information only. Not veterinary advice. Grades reflect published dog research and reviewer consensus, not marketing.