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Evidence DatabaseSaved evidence
Claim evidence

Meaningful benefit only in EPI-diagnosed dogs

Grade CLimited or mixed evidenceSave claim
Ingredient: Digestive Enzymes · gut

Plain-language summary

Otherwise limited benefit in normal dogs on complete diets.

About the ingredient

Cited studies (3)

Canine studies
  • A review: Pancreatic enzymes in the treatment of chronic pancreatic insufficiency in companion animals.
    Szkopek D, Pierzynowski SG, Pierzynowska K, Zaworski K, Kondej A, Wychowański P, Konieczka P, Seklecka B, Donaldson J, Jank M, Woliński J · Journal of veterinary internal medicine · 2024
    Save studyD
    Study summary
    Very limited quality
    Design score 2/11
    Design
    Journal Article; Review
    Species
    dog
    Sample size
    Not reported
    Duration
    Not reported
    Controls / blinding
    Not reported
    Funding
    Not reported
    Strengths
    • Conducted in dogs
    Limitations
    • Sample size not recorded
    • No control group recorded
    • Study duration not recorded

    Relevance to this claim: Ingredient-level evidence for Digestive Enzymes

    DOI: 10.1111/jvim.17096
  • Sulfation in dog.
    Tsoi C, Swedmark S · Current drug metabolism · 2005
    Save studyD
    Study summary
    Very limited quality
    Design score 2/11
    Design
    Journal Article; Review
    Species
    dog
    Sample size
    Not reported
    Duration
    Not reported
    Controls / blinding
    Not reported
    Funding
    Not reported
    Strengths
    • Conducted in dogs
    Limitations
    • Sample size not recorded
    • No control group recorded
    • Study duration not recorded

    Relevance to this claim: Ingredient-level evidence for Digestive Enzymes

    DOI: 10.2174/1389200054021816
  • Canine Gaucher disease--the enzymic defect.
    Van De Water NS, Jolly RD, Farrow BR · The Australian journal of experimental biology and medical science · 1979
    Save studyC
    Study summary
    Very limited quality
    Design score 2/11
    Design
    Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
    Species
    dog
    Sample size
    Not reported
    Duration
    Not reported
    Controls / blinding
    Not reported
    Funding
    Not reported
    Strengths
    • Conducted in dogs
    Limitations
    • Sample size not recorded
    • No control group recorded
    • Study duration not recorded

    Relevance to this claim: Ingredient-level evidence for Digestive Enzymes

    DOI: 10.1038/icb.1979.56

Products in our catalog with Digestive Enzymes (3)

Educational information only. Not veterinary advice. Grades reflect published dog research and reviewer consensus, not marketing.