Give orally daily or as directed by your veterinarian. Body Weight 1-30 lbs: 1/4 tsp daily 31-60 lbs: 1/2 tsp daily 61-90 lbs: 3/4 tsp daily 91+ lbs: 1 tsp daily Oral Probiotics contains a small amount of non-decolorized whole leaf aloe vera extract. California includes this specific form of aloe on its Proposition 65 list, so we provide the warning as a conservative compliance measure. That does not mean Oral Probiotics has been found to be unsafe. Proposition 65 warnings are based on potential human exposure to a listed substance, not simply on whether an ingredient appears in a formula. Oral Probiotics is made for dogs, aloe represents only a small part of the formula, and the amount handled by a person during normal use is extremely limited. California has not established a straightforward safe harbor exposure level for this form of aloe. As a result, proving that a warning is unnecessary can require expensive, product-specific testing and legal analysis. Many companies therefore provide a warning even when normal exposure is likely to be very low. California’s listing was based largely on a two year laboratory study in which rats continuously drank water containing comparatively high concentrations of aloe extract. That is very different from the small, measured amount included in a serving of Oral Probiotics. The same study did not find evidence of carcinogenic activity in mice. Aloe vera is a natural plant ingredient with a long history of use. We include it as one part of Oral Probiotics’ digestive support formula, where it helps support and soothe the gastrointestinal tract. The Proposition 65 warning is a legal disclosure. It is not a finding that Oral Probiotics causes cancer, is contaminated or is unsafe for dogs when used as directed. It’s just required in California.